Biomedicine and Chemical Sciences
2023, Volume 2, Issue 4 : 1-11 doi: https://doi.org/10.5281/zenodo.15282922
Research Article
Juvenile Idiopathic Arthritis (JIA)
Mohammed J. Al-Obaidi
 ,
Fadhaa O. Samer
 ,
Sinai W. Mohammed
 ,
Maysaa K. Al-Malkey
DOI : https://doi.org/10.5281/zenodo.15282922
Received
Aug. 19, 2023
Revised
Sept. 22, 2023
Accepted
Sept. 23, 2023
Published
Oct. 1, 2023
Abstract

Juvenile idiopathic arthritis (JIA) is a common type of arthritis in children and adolescents. This observational study was conducted in Baghdad (2019–2021). Records of JIA patients (n = 66) were documented from the teaching hospital in Al-Rusafa and Kadhimiya teaching hospital in Al-Karkh. JIA was categorised into 5 groups: Oligo JIA-Extended (OJIA-E) (n=16), OJIA-Persistence (OJIA-P) (n=15), Poly JIA (PJIA) (n=29), Systemic JIA (SJIA) (n=3), and Enthesitis-related Arthritis (ERA) (n=4). The Juvenile Arthritis Disease Activity Score-27 (JADAS 27) was used to measure disease activity for several months. JIA distribution in males and females (45.5% and 54.5%), respectively. The highest frequency of JIA type was observed in the age group 1-4 years with Oligo P (75%). Positive ANA test cases were found in 4 cases only. Four types of drugs and three types of biological drugs were found to be used to treat JIA. JADAS ranged from (8.1±5.7) to (19.4±8.6) with significant differences (p<0.05). Significant differences were noticed among the types of JIA in some blood tests and liver enzymes. The incidence of JIA decreased from 0.10/ 100000 to 0.005/ 100000. JIA with MTX, DMARDS duration, Steroid dosage, and JADAS all showed significant differences. There were no discernible differences in JIA with age, gender, disease duration, quantity of DMARDS, and blood tests.

Keywords
ANA
DMARDS
Juvenile idiopathic arthritis
Oligoarticular
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