Biomedicine and Chemical Sciences
2023, Volume 2, Issue 4 : 33-45 doi: https://doi.org/10.5281/zenodo.15287978
Research Article
Metabolic Engineering of Microbial Cell Factories for Sustainable Biomanufacturing
Azeemat Olanrewaju Olayiwola
 ,
Abubakar Dalhatu
 ,
Olutayo Micheal Oyewole
 ,
Grace Oluwasikemi Oke
 ,
Tolulope Joseph Ogunniyi
 ,
Adekunle Fiyin Ademikanra
DOI : https://doi.org/10.5281/zenodo.15287978
Received
Aug. 18, 2023
Revised
Sept. 22, 2023
Accepted
Sept. 25, 2023
Published
Oct. 1, 2023
Abstract

Metabolic engineering is essential for the development of microbial cell factories to produce biomolecules from low-value renewable substrates. This role helps advance the development of ecologically responsible and commercially robust chemical industries, including biofuels and high-value compounds like medicines. The ability of microbial cell factories to generate a wide variety of substances sustainably, therefore satisfying modern commodity needs, has piqued the scientific community's attention. The goal of metabolic engineering is to convert different microorganisms into efficient cell factories to produce desired products, and it has been used for decades to develop novel metabolic pathways and alter pre-existing ones with the help of system biology, synthetic biology, and evolutionary engineering.

Keywords
Biofuels
Cell factories
Metabolic engineering
Microbial cell
Microorganisms
Synthetic biology
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